Researcher Develops Innovative Device for Early Cancer Detection

A childhood experience with cancer has inspired a South Island researcher to develop groundbreaking technology for the early detection of cancer. Dr. Judy Ann Cocadiz, affiliated with the University of Otago, has received a three-year, $300,000 post-doctoral fellowship from the Cancer Society to support her work on an innovative diagnostic tool aimed at identifying early-stage cancers more accurately.

Dr. Cocadiz’s research focuses on circulating tumour DNA (ctDNA), which are fragments of DNA released into the bloodstream by cancer cells. The presence of ctDNA increases as cancer advances, making it a crucial indicator for diagnosis and monitoring.

Innovative Device for Accurate Diagnoses

Currently, doctors analyze ctDNA by drawing blood from patients, typically around 8-10 ml. However, in the case of early-stage cancers, this amount may yield insufficient ctDNA, making diagnosis challenging. Dr. Cocadiz explained, “It is like looking for a needle in a haystack.”

To address this issue, she is developing a small device that can be inserted into a blood vessel, functioning as a “sieve” to capture ctDNA over a brief period. This approach aims to provide a less invasive and more effective way to detect cancers early and monitor for any recurrence post-treatment.

“The device would be inserted similarly to an intravenous line, allowing us to collect ctDNA without needing to draw excessive blood from the patient,” Cocadiz added. This method could significantly reduce discomfort for patients, particularly vulnerable groups such as children or the elderly.

While the research remains in the proof of concept stage, Cocadiz is optimistic about its potential impact. “Getting this device into clinical use will take years, but I am really optimistic about where this research is heading,” she stated.

A Personal Journey Towards Cancer Research

Dr. Cocadiz’s passion for cancer research traces back to her childhood in the Philippines. At just five years old, she noticed that her best friend frequently had unexplained bruises. Her concern led to a visit to the doctor, where her friend was diagnosed with early-stage leukaemia and received prompt treatment.

Reconnecting with her friend earlier this year, Cocadiz was delighted to see him healthy and thriving. This pivotal experience shaped her career aspirations, leading her to pursue a path in cancer research rather than becoming a doctor.

“Everything just kind of fell into place, and I am really glad I ended up in cancer research,” she reflected.

Dr. Cocadiz expresses gratitude for the support from the Cancer Society, recognizing that their funding not only aids her research but also contributes significantly to the early stages of her career. As she advances her work, the hope is that this innovative device will enhance the accuracy of cancer diagnoses and ultimately improve patient outcomes.